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Posts Tagged ‘inflammation in COPD’

Inflammation COPD is characterised by the presence of CD+8 T-cells and macrophages in bronchial biopsies and an abundance of neutrophils in sputum. these tissue findings are contrast to asthma,where eosinophils are the dominant cell types.
interestingly,during exacerbations of mild COPD,a change in airway inflammation has been reported with increase in sputum eosinophuls. the rise in sputum eosinophils has been attributed to an increase in the expression. the benefits of steroid therapy during COPD exacerbation  can be explained by its impact on RANTES,a steroid sensitive eosinophils cytokine. Read the rest of this entry »